Thank you for all your comments, they are very helpful indeed.
Glad to hear that

If you are saying that an item considered redundant is merely rendered inactive by unchecking the particular box on the output table (all boxes are checked by default) and if there is any problem, simply rechecking it again to restore the file into active service, then fine, that sounds easy. I do not see any particular risk in doing that, providing the unchecked box or file is still shown on future runs unchecked and not excluded.
The only one risk is that you need to be sure what file are you unchecking. As you see, you can make there many operations. Semi-advanced user is able to display even more entries there, including critical system ones. Unchecking even one of them may be very harmful.
With that arrangement - similar to CCleaner start lists - nobody can possibly do any harm to the registry. It is a perfectly safe procedure and extremely user friendly.
If this is the case, then Autoruns for Windows is a superb program which does not need a user with a Masters Degree in Computer Science and can be used by ordinary foot sloggers like me.
I agree about being user friendly

But once again, extra precautions are mandatory when dealing with system ones. Other entries (especially the ones in Run key can be switched off to improve the system boot-up. Of course some of them are needed, like audio card drivers and others. For example on my machine startup looks like this:
HKLM\SOFTWARE\Wow6432Node\Microsoft\Windows\CurrentVersion\Run 2013-11-18 19:48
HDAudDeck VIA HD Audio CPL VIA c:\program files (x86)\via\viaudioi\vdeck\vdeck.exe 2012-08-09 10:22
SunJavaUpdateSched Java(TM) Update Scheduler Oracle Corporation c:\program files (x86)\common files\java\java update\jusched.exe 2013-07-02 17:16
HKCU\Software\Microsoft\Windows\CurrentVersion\Run 2013-06-05 15:57
SandboxieControl Sandboxie Control Sandboxie Holdings, LLC c:\program files\sandboxie\sbiectrl.exe 2013-10-16 14:07
C:\Users\User\AppData\Roaming\Microsoft\Windows\Start Menu\Programs\Startup 2013-10-24 13:25
Dropbox.lnk Dropbox Dropbox, Inc. c:\users\user\appdata\roaming\dropbox\bin\dropbox.exe 2013-06-28 23:12
Once more, if you're unsure about something when dealing with entries, ask in the forum. Staff here will tell you what should be left alone and what can be removed in a perfectly safe manner

The only fact is that I deleted an obvious rubbish file. It disappeared from the list, BUT it never showed up on a re-run. GONE ! How do we then recover that then ? I cannot find it. Where is this restore feature ? Without it, a computer disaster is a certainty.
Sorry, but I don't understand:
You mean that you deleted an entry to an obviously bad file?
Autoruns give you possibility to save settings (in the file menu at the top bar) and import them. Unfortunaltely I've never used this feature so I can't confirm to you how it exactly works.